Jobs
The following positions are available:
- Post-doctoral position available starting Jan 2009, in the Neural Injury Biomechanics and Repair Group in the Neuroengineering Laboratory at Georgia Tech.
PI: Michelle LaPlaca, Ph.D.
Funding: NIH R03.
Project Description: Augmentation of Plasma Membrane Repair for Treatment of Spinal Cord Injury. The objective is to assess the effects and mechanisms of plasma membrane repair mediated by citicoline, a membrane stabilizing agent that has been shown to be beneficial in many models of central nervous system disease. The overall hypothesis is that injury-induced membrane damage is detrimental to cell survival and functional outcome, but citicoline treatment can reduce these effects through facilitation of membrane preservation. Specifically, we will use a rodent contusion model to 1) determine a treatment dose of citicoline for spinal cord injury, defined by the ability to reseal compromised plasma membranes in cell bodies and axons and spare tissue, 2) assess possible mechanisms of citicoline-mediated repair, and 3) assess the ability of citicoline to mediate motor recovery.
Qualifications: The qualified candidate will have a background in neuroscience or injury biomechanics. Animal surgery experience is a must and it is preferred if the candidate has experience in spinal cord injury models or spine surgery. In addition, a strong base in biochemistry is a plus. The position will require good communication and writing skills, the ability to work on a dynamic team, as well as resourcefulness and independence. Please send CV and application letter via email.
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