Central Nervous System Regeneration
We are interested in understanding the role of astroglial scar in regenerative failure on the central nervous system. In particular we are exploring the contribution of chondroitin sulfate glycosaminoglycans (CS-GAGs), a major constituent of glial scar in vivo, to inhibition of CNS and PNS nerves.
We are also interested in investigating both intrinsic and extrinsic approaches to overcoming scar-related inhibition in the CNS. This project is currently funded by NIH (NINDS) R01 NS043486.
Sub-Projects
CS-GAG Mediated Inhibition of the Central Nervous System Regeneration
- Hyun-Jung Lee
Overcoming Chondroitin Sulfate-Dependent Inhibition in
the Central Nervous System
- Anjana Jain
Mechanism of CS-GAG Mediated Inhibition of Growth Cones
- Mary Millner