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Efstathios Karathanasis, PhD

Portrait of Efstathios Karathanasis

Assistant Professor
Department of Biomedical Engineering
Case Western Reserve University
Cleveland, OH

Faculty Site: http://bme.case.edu/faculty_staff/karathanasis/
Email: stathis [no spam] @case.edu

Education

  • Post-doctoral Fellowship, BME Neurolab, Georgia Institute of Technology, Atlanta, GA 2009
  • Ph.D., Chemical Engineering, University of Houston, Houston, TX, 2005
  • B.S. Chemical Engineering, Aristotle University, Thessaloniki, Greece, 1999

Research

My research interests lie in the intersection of nanotechnology with anatomical, functional and molecular imaging to design nanoscale contrast agents enabling patient-specific therapy. (project details)

Selected Publications

  1. E. Karathanasis, L. Chan, S.R. Balusu, C.J. D'Orsi, A.V. Annapragada, I. Sechopoulos, R.V. Bellamkonda, Multifunctional nanocarriers for mammographic quantification of tumor dosing and prognosis of breast cancer therapy, Biomaterials (in press)
  2. E. Karathanasis, S. Suryanarayanan, S.R. Balusu, K. McNeeley, I. Sechopoulos, A. Karellas, A.V. Annapragada, R.V. Bellamkonda, Imaging nanoprobe for prediction of nanoparticle chemotherapy using mammography, Radiology 2008 (in press)
  3. E. Karathanasis, J. Park, A. Agarwal, V. Patel, F. Zhao, A.V. Annapragada, X. Hu, R.V. Bellamkonda, MRI mediated, non-invasive tracking of intratumoral distribution of nanocarriers in rat glioma, Nanotechnology 19 315101 (9pp) 2008 (PDF)
  4. E. Karathanasis, K. McNeeley, A. Agarwal, A.V. Annapragada, R.V. Bellamkonda, MR trackable, chemotherapeutic nanoparticles for patient specific glioma therapy, Microscopy and Microanalysis 13(Suppl 2) (2007) 44-45
  5. E. Karathanasis, A. Agarwal, A.V. Annapragada, Triggered release of post-administered drugs, In: Handbook of Particulate Drug Delivery, R. Kumar Ed., American Scientific Publishers 2007, 243-260
  6. E. Karathanasis, R. Bhavane, A.V. Annapragada, Glucose-sensing pulmonary delivery of human insulin to the systemic circulation of rats, International Journal of Nanomedicine 2(3) (2007) 501-513
  7. R. Bhavane, E. Karathanasis, A.V. Annapragada, Triggered release of ciprofloxacin from nanostructured agglomerated vesicles, International Journal of Nanomedicine 2(3) (2007) 407-418
  8. E. Karathanasis, R. Bhavane, A.V. Annapragada, Triggered release of inhaled insulin from the agglomerated vesicles: Pharmacodynamic studies in rats, Journal of Controlled Release 113(2) (2006) 117-127
  9. E. Karathanasis, A. Ayyagari, R. Bhavane, R. Bellamkonda, A.V. Annapragada, Preparation of in vivo cleavable agglomerated liposomes suitable for modulated pulmonary drug delivery, Journal of Controlled Release 103(1) (2005) 159-175
  10. R. Bhavane, E. Karathanasis, A.V. Annapragada, Agglomerated Vesicle Technology: A new class of particles for controlled and modulated pulmonary drug delivery, Journal of Controlled Release 93(1) (2003) 15-28

Press

On the imaging nanoprobe for prediction of chemotherapy outcome

On the multifunctional nanoparticle for prediction of chemotherapy

On the MR-trackable nanocarrier

On the glucose-sensitive nanostructured inhalable insulin particle