Chondroitin Sulfate GAG mediated inhibition of Growth Cones (abstract)
1R01 NS043486-01A1 (PI: Bellamkonda) Dates: 12/01/2002 - 11/30/2006
Source: National Institutes of Health
The major goals of this project are to define biochemical properties of scar tissue,
particularly the GAG part of chondroitin sulfate proteoglycans (CSPGs), and study their
effects on peripheral and central growth cones in vitro. Aim 2 seeks to elicit the mechanism
by which CS-GAGs may inhibit growth cones.
Collaborators: Robert McKeon, Ph.D., Emory University; Jerry Silver,
Ph.D. - Case Western Reserve University; Diane Snow, Ph.D. - University of Kentucky; Harihara
Baskaran, Ph.D. - Case Western Reserve University; Vincent Hascall, Ph.D. - Cleveland Clinic
Foundation